Health Scope

Published by: Kowsar

Effects of Exposure to Cigarette Smoke on Distortion-Product Otoacoustic Emissions in Rats

Raheleh Hashemi Habybabady 1 , Seyed Bagher Mortazavi 1 , * , Ali Khavanin 1 and Ramazan Mirzaei 2
Authors Information
1 Department of Occupational Health Engineering, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, IR Iran
2 Department of Environmental and Occupational Health Engineering, School of Health, Social Determinants of Health Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
Article information
  • Health Scope: August 2017, 6 (3); e15175
  • Published Online: July 22, 2016
  • Article Type: Research Article
  • Received: August 9, 2016
  • Revised: October 26, 2016
  • Accepted: November 10, 2016
  • DOI: 10.5812/jhealthscope.15175

To Cite: Hashemi Habybabady R, Mortazavi S B, Khavanin A, Mirzaei R. Effects of Exposure to Cigarette Smoke on Distortion-Product Otoacoustic Emissions in Rats, Health Scope. 2017 ; 6(3):e15175. doi: 10.5812/jhealthscope.15175.

Copyright © 2016, Journal of Health Scope. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
  • 1. Johnson AC, Morata TC. Occupational exposure to chemicals and hearing impairment. Gothenburg, Sweden: University of Gothenburg & authors; 2010.
  • 2. van der Vaart H, Postma DS, Timens W, ten Hacken NH. Acute effects of cigarette smoke on inflammation and oxidative stress: a review. Thorax. 2004;59(8):713-21. doi: 10.1136/thx.2003.012468. [PubMed: 15282395].
  • 3. Ferrite S, Santana V. Joint effects of smoking, noise exposure and age on hearing loss. Occup Med (Lond). 2005;55(1):48-53. doi: 10.1093/occmed/kqi002. [PubMed: 15699090].
  • 4. Barone JA, Peters JM, Garabrant DH, Bernstein L, Krebsbach R. Smoking as a risk factor in noise-induced hearing loss. J Occup Med. 1987;29(9):741-5. [PubMed: 3681506].
  • 5. Fabry DA, Davila EP, Arheart KL, Serdar B, Dietz NA, Bandiera FC, et al. Secondhand smoke exposure and the risk of hearing loss. Tob Control. 2011;20(1):82-5. doi: 10.1136/tc.2010.035832. [PubMed: 21081307].
  • 6. Jacobsen LK, Slotkin TA, Mencl WE, Frost SJ, Pugh KR. Gender-specific effects of prenatal and adolescent exposure to tobacco smoke on auditory and visual attention. Neuropsychopharmacology. 2007;32(12):2453-64. doi: 10.1038/sj.npp.1301398. [PubMed: 17375135].
  • 7. Mizoue T, Miyamoto T, Shimizu T. Combined effect of smoking and occupational exposure to noise on hearing loss in steel factory workers. Occup Environ Med. 2003;60(1):56-9. doi: 10.1136/oem.60.1.56. [PubMed: 12499458].
  • 8. Rogha M, Hashemi M, Askari N, Abtahi SH, Sepehrnejad M, Nilforoush MH. Cigarette smoking effect on human cochlea responses. Adv Biomed Res. 2015;4:148. doi: 10.4103/2277-9175.161575. [PubMed: 26380233].
  • 9. Virokannas H, Anttonen H. Dose-response relationship between smoking and impairment of hearing acuity in workers exposed to noise. Scand Audiol. 1995;24(4):211-6. doi: 10.3109/01050399509047538. [PubMed: 8750748].
  • 10. Cruickshanks KJ, Klein R, Klein BE, Wiley TL, Nondahl DM, Tweed TS. Cigarette smoking and hearing loss: the epidemiology of hearing loss study. JAMA. 1998;279(21):1715-9. doi: 10.1001/jama.279.21.1715. [PubMed: 9624024].
  • 11. Nakanishi N, Okamoto M, Nakamura K, Suzuki K, Tatara K. Cigarette smoking and risk for hearing impairment: a longitudinal study in Japanese male office workers. J Occup Environ Med. 2000;42(11):1045-9. doi: 10.1097/00043764-200011000-00001. [PubMed: 11094781].
  • 12. Paschoal CP, Azevedo MF. Cigarette smoking as a risk factor for auditory problems. Braz J Otorhinolaryngol. 2009;75(6):893-902. doi: 10.1016/S1808-8694(15)30556-5. [PubMed: 20209294].
  • 13. Siegelaub AB, Friedman GD, Adour K, Seltzer CC. Hearing loss in adults: relation to age, sex, exposure to loud noise, and cigarette smoking. Arch Environ Health. 1974;29(2):107-9. doi: 10.1080/00039896.1974.10666542. [PubMed: 4835178].
  • 14. Starck J, Toppila E, Pyykko I. Smoking as a risk factor in sensory neural hearing loss among workers exposed to occupational noise. Acta Otolaryngol. 1999;119(3):302-5. doi: 10.1080/00016489950181288. [PubMed: 10380732].
  • 15. Mom T, Bonfils P, Gilain L, Avan P. Vulnerability of the gerbil cochlea to sound exposure during reversible ischemia. Hear Res. 1999;136(1-2):65-74. doi: 10.1016/S0378-5955(99)00109-4. [PubMed: 10511625].
  • 16. Fechter LD, Chen GD, Rao D, Larabee J. Predicting exposure conditions that facilitate the potentiation of noise-induced hearing loss by carbon monoxide. Toxicol Sci. 2000;58(2):315-23. doi: 10.1093/toxsci/58.2.315. [PubMed: 11099644].
  • 17. Johnson AC, Juntunen L, Nylen P, Borg E, Hoglund G. Effect of interaction between noise and toluene on auditory function in the rat. Acta Otolaryngol. 1988;105(1-2):56-63. doi: 10.3109/00016488809119446. [PubMed: 3341162].
  • 18. Khavanin A, Mortazavi SB, Mirzaei R, Imani H, Kazemnejad A, Akbari M. The comparison of effects of toluene, especially noise and toluene along with noise per Auditory Brain Stem response on rabbit [In Persian]. Tabib-E-Shargh. 2007;9(3):171-80.
  • 19. Lataye R, Campo P. Combined effects of a simultaneous exposure to noise and toluene on hearing function. Neurotoxicol Teratol. 1997;19(5):373-82. doi: 10.1016/s0892-0362(97)00049-4. [PubMed: 9380004].
  • 20. Lataye R, Campo P, Loquet G. Combined effects of noise and styrene exposure on hearing function in the rat. Hear Res. 2000;139(1-2):86-96. doi: 10.1016/S0378-5955(99)00174-4. [PubMed: 10601715].
  • 21. Liu S, Zhang K, Wu S, Ji X, Li N, Liu R, et al. Lead-induced hearing loss in rats and the protective effect of copper. Biol Trace Elem Res. 2011;144(1-3):1112-9. doi: 10.1007/s12011-011-9142-6. [PubMed: 21750944].
  • 22. Motalebi Kashani M, Khavanin A, Alameh A, Mirzaei R, Akbari M. Effect of simultaneous noise and carbon monoxide exposure on rabbits' auditory brain stem response [In Persian]. Feyz. 2010;13(4):261-70.
  • 23. Rao DB, Fechter LD. Increased noise severity limits potentiation of noise induced hearing loss by carbon monoxide. Hear Res. 2000;150(1-2):206-14. doi: 10.1016/S0378-5955(00)00202-1. [PubMed: 11077204].
  • 24. Young JS, Upchurch MB, Kaufman MJ, Fechter LD. Carbon monoxide exposure potentiates high-frequency auditory threshold shifts induced by noise. Hear Res. 1987;26(1):37-43. doi: 10.1016/0378-5955(87)90034-7. [PubMed: 3558142].
  • 25. Jardim JR, Bizeto L, Fleig Mayer A, Camelier A, Rosa FW, Oliveira D, et al. [An inhalation chamber model for controlled studies of tobacco smoke toxicity in rodents]. Arch Bronconeumol. 2010;46(9):455-8. doi: 10.1016/j.arbres.2010.05.012. [PubMed: 20624668].
  • 26. Prusaczyk WK, Fischer GJ. A small-animal inhalation chamber for short-to-intermediate term exposure. Behav Res Methods Instrum. 1983;15(3):369-73. doi: 10.3758/bf03203661.
  • 27. Laskin S, Drew RT. An inexpensive portable inhalation chamber. Am Ind Hyg Assoc J. 1970;31(5):645-6. doi: 10.1080/0002889708506307. [PubMed: 5275099].
  • 28. O'Shaughnessy PT, Achutan C, O'Neill ME, Thorne PS. A small whole-body exposure chamber for laboratory use. Inhal Toxicol. 2003;15(3):251-63. doi: 10.1080/08958370304504. [PubMed: 12579456].
  • 29. Shraideh ZA, Awaida W, Najjar H. A modified smoking machine for monitoring the effect of tobacco smoke on albino rats. Jordan J Biol Sci. 2011;4(2):109-12.
  • 30. Wong BA. Inhalation exposure systems: design, methods and operation. Toxicol Pathol. 2007;35(1):3-14. doi: 10.1080/01926230601060017. [PubMed: 17325967].
  • 31. Guerin MR. The FTC cigarette test method for determining tar, nicotine, and carbon monoxide yields of U.S. cigarettes. 7 ed. US: Department of health and human services; 1996.
  • 32. Hatzopoulos S, Petruccelli J, Laurell G, Finesso M, Martini A. Evaluation of anesthesia effects in a rat animal model using otoacoustic emission protocols. Hear Res. 2002;170(1-2):12-21. doi: 10.1016/S0378-5955(02)00448-3. [PubMed: 12208537].
  • 33. Negley C, Katbamna B, Crumpton T, Lawson GD. Effects of cigarette smoking on distortion product otoacoustic emissions. J Am Acad Audiol. 2007;18(8):665-74. doi: 10.3766/jaaa.18.8.4. [PubMed: 18326153].
  • 34. Mehrparvar AH, Davari MH, Mollasadeghi A, Vahidi MR, Mostaghaci M, Bahaloo M, et al. Hearing Loss due to Carbon Monoxide Poisoning. Case Rep Otolaryngol. 2013;2013:940187. doi: 10.1155/2013/940187. [PubMed: 23762709].
  • 35. Dengerink HA, Lindgren FL, Axelsson A. The interaction of smoking and noise on temporary threshold shifts. Acta Otolaryngol. 1992;112(6):932-8. doi: 10.3109/00016489209137493. [PubMed: 1481663].
  • 36. Howard G, Wagenknecht LE, Burke GL, Diez-Roux A, Evans GW, McGovern P, et al. Cigarette smoking and progression of atherosclerosis: The Atherosclerosis Risk in Communities (ARIC) Study. JAMA. 1998;279(2):119-24. doi: 10.1001/jama.279.2.119. [PubMed: 9440661].
  • 37. Lacerda A, Leroux T, Morata T. [Ototoxic effects of carbon monoxide exposure: a review]. Pro Fono. 2005;17(3):403-12. doi: 10.1590/S0104-56872005000300014. [PubMed: 16389797].
  • 38. Dugan LL, Choi DW. Basic Neurochemistry: Molecular, Cellular and Medical Aspects. 6 ed. Washington: University: Department of Neurology; 1999.
  • 39. Vannucci SJ, Hagberg H. Hypoxia-ischemia in the immature brain. J Exp Biol. 2004;207(Pt 18):3149-54. doi: 10.1242/jeb.01064. [PubMed: 15299036].
  • 40. Wild DC, Brewster MJ, Banerjee AR. Noise-induced hearing loss is exacerbated by long-term smoking. Clin Otolaryngol. 2005;30(6):517-20. doi: 10.1111/j.1749-4486.2005.01105.x. [PubMed: 16402976].
  • 41. Ahn JH, Joo HS, Suh JK, Kim H, So HS, Chung JW. Effects of cigarette smoking on hearing recovery from noise-induced temporary hearing threshold shifts in mice. Otol Neurotol. 2011;32(6):926-32. doi: 10.1097/MAO.0b013e318225575a. [PubMed: 21725268].
  • 42. Aftab A, Quraishi S. Etiological causes of reversible sensorineural hearing loss. Internet J Otorhinolaryngology. 2006;4(2).
  • 43. Morrow JD, Frei B, Longmire AW, Gaziano JM, Lynch SM, Shyr Y, et al. Increase in circulating products of lipid peroxidation (F2-isoprostanes) in smokers. Smoking as a cause of oxidative damage. N Engl J Med. 1995;332(18):1198-203. doi: 10.1056/NEJM199505043321804. [PubMed: 7700313].
  • 44. Abdel-Hafez AM, Elgayar SA, Husain OA, Thabet HS. Effect of nicotine on the structure of cochlea of guinea pigs. Anat Cell Biol. 2014;47(3):162-70. doi: 10.5115/acb.2014.47.3.162. [PubMed: 25276475].
  • 45. Nordmann AS, Bohne BA, Harding GW. Histopathological differences between temporary and permanent threshold shift. Hear Res. 2000;139(1-2):13-30. doi: 10.1016/S0378-5955(99)00163-X. [PubMed: 10601709].
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